Better Poster (big finding)

\documentclass[25pt,a0paper,landscape]{tikzposter}
\usepackage{amsmath}
\usetheme{Simple}

\title{}\author{}\institute{}

\begin{document}

\begin{columns}
\column{0.25}
\block{Study}{
  What we did, in plain words. Methods details live in the QR-linked paper,
  not on the poster.
}
\block{Data}{
  Where the data came from and how much of it there is.
}

\column{0.5}
\block{}{
  \vspace{6cm}
  \begin{center}
    {\fontsize{72}{80}\selectfont\bfseries The one-sentence finding\\ goes here.}
  \end{center}
  \vspace{6cm}
}

\column{0.25}
\block{Evidence}{
  The single most convincing chart or table.
}
\block{So what}{
  What a practitioner should do differently after reading this.
}
\end{columns}

\end{document}